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To prevent development of stomach ulcers, which may sometimes be caused by arthritis medicines that are called non-steroidal anti-inflammatory drugs (NSAIDs).
To prevent bleeding in the stomach or upper intestine in hospital patients after surgery.
CYTOTEC makes your stomach produce less acid, and it helps your stomach protect itself against damage from acid and certain other substances, such as NSAIDs.
The active ingredient in CYTOTEC is called misoprostol. Misoprostol is very similar to a group of substances called prostaglandins, which occur naturally in the stomach and other parts of the body. When the amount of these natural prostaglandins is lower than normal, there is a risk that ulcers may occur in the stomach or duodenum. This reduction in prostaglandins is often a side effect of NSAIDs. CYTOTEC can replace prostaglandins and help to prevent ulcers, or help heal the ulcer if you already have one. If you are taking an NSAID, CYTOTEC helps protect your stomach while you continue to receive the benefit of pain relief and reduction in joint swelling from your arthritis medicine.
Your doctor, however, may prescribe CYTOTEC for another purpose.
Ask your doctor if you have any questions about why CYTOTEC has been prescribed for you.
There is no evidence that CYTOTEC is addictive. 
The effects of CYTOTEC may be harmful to a developing baby (fetus).
If it is possible for you to become pregnant, you should use adequate contraception while you are taking CYTOTEC. Examples of adequate contraception are oral contraceptives (“the pill”) or intra-uterine devices (IUDs).
CYTOTEC must not be used by pregnant women as it may cause miscarriage, and this could lead to potentially dangerous bleeding, hospitalisation, surgery, infertility or death. You should not become pregnant while taking CYTOTEC. 
The usual dosage of CYTOTEC is one tablet two, three or four times a day.
CYTOTEC is best taken with food. Do not take CYTOTEC on an empty stomach.
Follow your doctor’s instructions exactly, on how much CYTOTEC to take, and for how long to take it. If you are taking an NSAID, CYTOTEC may be prescribed for as long as you are taking the NSAID, whether or not you have stomach pain or other symptoms of ulcers. Some ulcers are painless, particularly those caused by NSAIDs.